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Updated: Jun 2, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
2-(2-Hy-droxy-3-meth-oxy-phen-yl)-6H-perimidin-6-one
Abstract:
The mol-ecule of the title perimidine derivative, C(18)H(12)N(2)O(3), is essentially planar, the dihedral angle between the benzene and perimidine rings being 3.25 (5)°. The hy-droxy and meth-oxy groups lie in the plane of the benzene ring to which they are bound [O-C-C-C = 179.96 (11)° and C-O-C-C = -177.96 (12)°]. An intra-molecular O-H⋯N inter-action generates an S(6) ring motif. In the crystal, mol-ecules are linked by pairs of C-H⋯O inter-actions into dimers, which generate S(16) ring motifs. These dimers are arranged into sheets parallel to the ac plane and further stacked down the b axis by π-π inter-actions, with centroid-centroid distances in the range 3.5066 (8)-3.7241 (7) Å.
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