Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure and Nomenclature of Ethers02:28

Structure and Nomenclature of Ethers

Structure and Bonding
Ethers are organic compounds with an ether functional group which is characterized by an oxygen atom connected to two — identical or different — alkyl, aryl, or vinyl groups. The C–O–C linkage in dimethyl ether — the simplest ether — has an approximately tetrahedral bond angle of 110.3 degrees. The oxygen atom is sp3- hybridized, with the C–O distance being about 140 pm.
Classification of Ethers
Based on their attached substituent groups, ethers can be classified into two...
Structure and Nomenclature of Epoxides02:38

Structure and Nomenclature of Epoxides

Cyclic ethers are heterocyclic compounds with an oxygen atom in the ring along with carbon atoms. They are named depending on the number of carbon atoms present in their ring system. Cyclic ethers with a three-membered ring system are called “oxirane”, four-membered ring systems as “oxetane”, five-membered ring systems as “oxolane”, and six-membered ring systems as “oxane”. The cyclic structure of these rings imposes angle strain, and this strain is more in the ring having a smaller number of...
Preparation of Epoxides03:00

Preparation of Epoxides

Overview
Epoxides result from alkene oxidation, which can be achieved by a) air, b) peroxy acids, c) hypochlorous acids, and d) halohydrin cyclization.
Epoxidation with Peroxy Acids
Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of peroxy acids to...
Structure and Nomenclature of Alcohols and Phenols02:23

Structure and Nomenclature of Alcohols and Phenols

Overview
Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
As with other organic compounds, alcohols and phenols...
Acidity and Basicity of Alcohols and Phenols02:36

Acidity and Basicity of Alcohols and Phenols

Like water, alcohols are weak acids and bases. This is attributed to the polarization of the O–H bond making the hydrogen partially positive. Moreover, the electron pairs on the oxygen atom of alcohol make it both basic and nucleophilic. Protonation of an alcohol converts hydroxide, a poor leaving group, into water—a good one. The two acid–base equilibria corresponding to ethanol are depicted below.
Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mycoelectronics: Bioprinted living fungal bioelectronics for artificial sensation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Capillarisenol C, a novel bisphenol from Artemisia capillaris, induces ER stress-mediated cytotoxic autophagy in liver cancer cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2026
Same author

Resolving multiscale challenges in neuroscience: A frequency-aware network and benchmarks for live-cell and nuclear foci segmentation.

Journal of neuroscience methods·2026
Same author

A Benzophenanthrazine Schiff Base Fluorescent Probe for Selective Detection of Cu<sup>2</sup>.

Journal of fluorescence·2026
Same author

Exosomal miR-124 from M2 macrophages protects against hypertensive cardiac remodeling through suppression of Calpain-1.

International immunopharmacology·2026
Same author

Early postnatal antibiotic-associated gut microbiota alterations might promote long-term lipid metabolism via brown adipose tissue metabolic programming.

Gut microbes·2026

Related Experiment Video

Updated: Jun 2, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

1,2-Bis(2-meth-oxy-6-formyl-phen-oxy)ethane.

Hongqi Li1, Li Cai, Dongling Chen

  • 1Key Laboratory of Science & Technology of Eco-Textiles, Ministry of Education, College of Chemistry, Chemical Engineering & Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online
|April 28, 2011
PubMed
Summary

Researchers synthesized a novel organic compound, 3,3'-dimethoxy-2,2'-(ethane-1,2-diyldioxy)dibenzaldehyde, linking two vanillin units. The study details its preparation and the specific molecular geometry of the resulting structure.

More Related Videos

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
08:12

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
08:12

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers

Published on: December 16, 2022

Related Experiment Videos

Last Updated: Jun 2, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
08:12

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
08:12

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers

Published on: December 16, 2022

Area of Science:

  • Organic Chemistry
  • Crystallography

Background:

  • Vanillin derivatives are important building blocks in organic synthesis.
  • Understanding molecular structure is crucial for predicting chemical properties and reactivity.

Purpose of the Study:

  • To synthesize and characterize a novel dibenzaldehyde derivative.
  • To determine the solid-state structure of the title compound.

Main Methods:

  • Chemical synthesis involving ortho-vanillin and 1,2-dibromoethane.
  • Single-crystal X-ray diffraction analysis to elucidate molecular structure.

Main Results:

  • Successful synthesis of 3,3 -dimethoxy-2,2 -(ethane-1,2-diyldioxy)dibenzaldehyde.
  • The crystal structure revealed two vanillin units linked by an ethane-1,2-diyldioxy bridge.
  • A dihedral angle of 41.6(5)° was observed between the two benzene rings.

Conclusions:

  • The synthesis yielded the target compound with the expected linkage.
  • The determined dihedral angle provides insight into the molecule's conformation and potential interactions.