Related Experiment Video

Updated: Jun 2, 2026

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
06:52

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

Published on: October 30, 2018

Ethyl 3-oxo-2-(2-phenyl-hydrazinyl-idene)butano-ate: a re-determination

Satish Chandra Gupta, Deo Kumar Mandal, Asha Rani

    Acta Crystallographica. Section E, Structure Reports Online
    |April 28, 2011
    PubMed

    More Related Videos

    A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species08:12

    A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

    Published on: August 16, 2018

    Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate06:46

    Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

    Published on: June 21, 2017

    Related Concept Videos

    Hydroboration-Oxidation of Alkenes03:08

    Hydroboration-Oxidation of Alkenes

    In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
    Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration02:34

    Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration

    The rate of acid-catalyzed hydration of alkenes depends on the alkene's structure, as the presence of alkyl substituents at the double bond can significantly influence the rate.
    Reactions at the Benzylic Position: Oxidation and Reduction00:59

    Reactions at the Benzylic Position: Oxidation and Reduction

    The benzylic position describes the position of a carbon atom attached directly to a benzene ring. Benzene by itself does not undergo oxidation. In contrast, the benzylic carbon is quite reactive in the presence of strong oxidizing agents such as KMnO4 or H2CrO4. Therefore, alkylbenzenes are readily oxidized to benzoic acid, irrespective of the type of alkyl groups.
    Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids02:04

    Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

    Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.
    Electrophilic 1,2- and 1,4-Addition of HX to 1,3-Butadiene01:17

    Electrophilic 1,2- and 1,4-Addition of HX to 1,3-Butadiene

    The electrophilic addition of hydrogen halides such as HBr to alkenes and nonconjugated dienes gives a single product as per Markovnikov’s rule.
    Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide02:44

    Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

    Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.