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Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
Cellular Adaptation III: Hyperplasia01:26

Cellular Adaptation III: Hyperplasia

Hyperplasia is an increase in the number of cells in a tissue or organ due to enhanced cell division. It is an adaptive, controlled response to stimuli such as injury, hormones, or stress, involving mitosis to produce genetically identical cells and support tissue repair and regeneration.Tissue CapacityCertain tissues, including the epidermis, intestinal epithelium, bone marrow, and fibroblasts, have a high potential for hyperplasia. Others, such as bone, cartilage, and smooth muscle, show...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Cellular Adaptation IV: Dysplasia and Metaplasia

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Cellular Adaptation I: Introduction and Atrophy

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Related Experiment Video

Updated: Jun 2, 2026

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation
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Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation

Published on: February 15, 2018

Failure to thrive: an update.

Sarah Z Cole1, Jason S Lanham

  • 1Mercy Family Medicine Residency, St. John's Mercy Medical Center, St. Louis, MO, USA.

American Family Physician
|April 29, 2011
PubMed
Summary

Failure to thrive (FTT) in children stems from insufficient calorie intake or absorption. Early intervention with multidisciplinary support improves outcomes, though long-term cognitive effects remain uncertain.

Area of Science:

  • Pediatrics
  • Nutrition Science
  • Child Development

Background:

  • Failure to thrive (FTT) affects 5-10% of US children in primary care.
  • Defined by weight-for-age below 5th percentile or significant growth deceleration.
  • Most FTT cases result from inadequate caloric intake due to behavioral or psychosocial factors.

Purpose of the Study:

  • To review the evaluation and management of pediatric failure to thrive.
  • To highlight the importance of accurate caloric intake assessment.
  • To discuss treatment strategies and long-term implications.

Main Methods:

  • Review of clinical definitions and diagnostic indicators for FTT.
  • Emphasis on outpatient evaluation, focusing on dietary history.

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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

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  • Criteria for hospitalization and recommended multidisciplinary treatment approaches.
  • Main Results:

    • Single indicators for FTT have low predictive value.
    • Accurate assessment of eating habits is crucial for diagnosis.
    • Multidisciplinary treatment, including home nursing and nutritional counseling, enhances weight gain and parent-child interactions.

    Conclusions:

    • FTT evaluation prioritizes accurate caloric intake assessment over routine labs.
    • Hospitalization is reserved for refractory cases, suspected abuse, or severe caregiver impairment.
    • While short-term outcomes improve with intervention, long-term cognitive and academic impacts of FTT require further research.