Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reply by Authors.

The Journal of urology·2022

Same author

Computer-Generated R.E.N.A.L. Nephrometry Scores Yield Comparable Predictive Results to Those of Human-Expert Scores in Predicting Oncologic and Perioperative Outcomes.

The Journal of urology·2021

Same author

Re: Almassi et al.: Use of <sup>99m</sup>Tc-Sestamibi Single-photon Emission Computed Tomography / X-ray Computed Tomography in the Diagnosis of Hybrid Oncocytic / Chromophobe Tumor in a Pediatric Patient. (Urology 2018;113:206-208).

Urology·2018

Same author

Association between high visceral fat area and postoperative complications in patients with Crohn's disease following primary surgery.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2015

Same author

Short telomere syndrome and fibrosis.

QJM : monthly journal of the Association of Physicians·2015

Same author

Comparison of radiation dose and image quality from single-energy and dual-energy CT examinations in the same patients screened for hepatocellular carcinoma.

Clinical radiology·2014

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue

Investigations on the Ga(III) Complex of EOB-DTPA and Its ⁶⁸Ga Radiolabeled Analogue

Published on: August 17, 2016

Focal liver lesion detection and characterization with GD-EOB-DTPA.

A S Purysko¹, E M Remer, J C Veniero

¹Abdominal Imaging Section, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA. purysko@gmail.com

Clinical Radiology

|April 29, 2011

Summary

Magnetic resonance imaging (MRI) with gadoxetic acid disodium (Gd-EOB-DTPA) offers superior soft-tissue contrast for liver lesions. Familiarity with Gd-EOB-DTPA enhancement patterns in the hepatocyte phase is crucial for accurate interpretation of focal liver lesions.

More Related Videos

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

Related Experiment Videos

Last Updated: Jun 2, 2026

Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue

Investigations on the Ga(III) Complex of EOB-DTPA and Its ⁶⁸Ga Radiolabeled Analogue

Published on: August 17, 2016

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

Area of Science:

Radiology
Medical Imaging
Hepatology

Background:

Magnetic resonance imaging (MRI) provides superior soft-tissue contrast compared to computed tomography (CT) for liver lesion detection and characterization.
Gadoxetic acid disodium (Gd-EOB-DTPA) is a hepatobiliary-specific MRI contrast agent increasingly utilized in liver imaging.

Purpose of the Study:

To illustrate typical enhancement patterns of common liver lesions using Gd-EOB-DTPA in clinical practice.
To briefly explain the mechanism of action of Gd-EOB-DTPA.
To emphasize the importance of understanding the hepatocyte phase appearance of lesions.

Main Methods:

Review of existing literature on Gd-EOB-DTPA liver imaging.
Demonstration of characteristic enhancement patterns for common focal liver lesions.
Discussion of the mechanism of Gd-EOB-DTPA uptake and excretion.

Main Results:

Gd-EOB-DTPA demonstrates distinct enhancement patterns for various focal liver lesions.
Understanding the hepatocyte phase is critical for differentiating lesions.
The agent's mechanism involves uptake by functioning hepatocytes.

Conclusions:

Radiologists must be familiar with Gd-EOB-DTPA enhancement patterns, particularly in the hepatocyte phase.
Accurate interpretation of liver MRI with Gd-EOB-DTPA relies on recognizing lesion appearances.
This knowledge aids in avoiding misinterpretation of focal liver lesions.