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Updated: Jun 2, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Assessment of growth: variations according to references and growth parameters used
Marie-Françoise Rolland-Cachera1, Sandrine Péneau
1INSERM, U557, Bobigny, France. mf.cachera@uren.smbh.univ-paris13.fr
Insights
Different growth references significantly impact infant growth interpretation and obesity risk assessment. Awareness of chosen methods is crucial for accurate clinical and epidemiological evaluations.
Area of Science:
- Pediatric Growth Assessment
- Obesity Risk Prediction
- Public Health Nutrition
Background:
- Numerous studies link early childhood growth to future obesity risk.
- Significant variability exists in methodologies, particularly growth references and parameters used.
- Discrepancies in growth assessment can lead to differing interpretations and parental advice.
Purpose of the Study:
- To compare various international growth references against World Health Organization (WHO) standards.
- To evaluate the impact of different references and growth parameters on obesity risk prediction.
- To highlight the importance of consistent methodology in growth assessment.
Main Methods:
- Comparative analysis of national growth references (France, US CDC, Netherlands, Belgium, UK) with WHO standards.
- Examination of infant growth patterns (weight, length, BMI) across different age groups (0-3 months, 6+ months).
- Evaluation of epidemiologic and clinical studies assessing consequences of using different references.
Main Results:
- National references showed lower infant measurements than WHO standards in the first 3 months.
- After 6 months, national references generally exceeded WHO standards.
- Breastfed infants' growth aligned more closely with WHO standards, suggesting feeding practices influence reference differences.
- Use of different references led to significant variations in interpreting child growth and predicting obesity risk.
Conclusions:
- The choice of growth reference significantly alters the interpretation of infant growth trajectories.
- Weight and length gains are identified as potential parameters for predicting future obesity risk.
- Standardized and consistent methods for growth assessment are essential in clinical and epidemiological contexts.
Abstract:
Numerous studies have investigated associations between early growth and future risk of obesity, but the methods used varied considerably. Different growth references or parameters can be considered. Growth references from France, the United States (the Centers for Disease Control and Prevention), the Netherlands, Belgium, and the United Kingdom were compared with World Health Organization (WHO) standards. For the first 3 mo of life, all references showed markedly lower values for weight, length, and body mass index (BMI) compared with WHO standards, but after the age of 6 mo references were generally higher than WHO standards. Compared with nonbreastfed infants, the growth of breastfed infants was generally closer to that of WHO standards. Because data in the WHO standards were collected on infants who were breastfed, the difference between references and WHO standards might be mainly attributable to feeding practices. Epidemiologic and clinical studies evaluated the consequences of using either WHO standards or national references and showed differences according to the reference used. Analyses of children's weight curves by physicians showed significant differences in the interpretation of child growth and therefore in the advice given to parents. Finally, the effect of using different growth parameters to predict future risk of obesity was examined and showed that weight and length gains may be good candidates to study future risks. In conclusion, because the reference or parameters used to assess growth have an important effect on the interpretation of growth, it is crucial to be aware of the consequences of the methods used in clinical or epidemiologic contexts.
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