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Updated: Jun 2, 2026
07:56
Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
Published on: November 16, 2018
Stem cell therapy: a challenge to periodontist
Jayashree A Mudda1, Monika Bajaj
1Department of Periodontics, HKE Society's S N Institute of Dental Sciences and Research, Gulbarga, Karnataka, India. sndcg@yahoo.co.in
Summary
Periodontitis treatment aims to regenerate lost periodontal tissues. This review explores stem cells from dental tissues, like the periodontal ligament, for potential cell-based therapies to achieve complete periodontal regeneration.
Area of Science:
- Periodontal Medicine
- Regenerative Dentistry
- Stem Cell Biology
Background:
- Periodontitis involves inflammation and loss of periodontal tissues (ligament, cementum, bone).
- Current therapies (bone grafts, growth factors, membranes) aim for tissue regeneration.
- Stem cell research offers promising avenues for treating complex diseases.
Purpose of the Study:
- To review stem cells in medicine and dentistry.
- To explore their potential for periodontal regeneration.
Main Methods:
- Literature review of stem cell applications in medicine.
- Analysis of studies on stem cells in dental tissues, specifically periodontal ligament.
- Evaluation of cell-based therapy potential for periodontal regeneration.
Main Results:
- Stem cells are present in dental tissues, including the periodontal ligament.
- Studies confirm the presence of stem cells in dental tissues.
- Cell-based therapies are emerging for periodontal regeneration.
Conclusions:
- Stem cells hold significant potential for complete periodontal regeneration.
- Further research into stem cell applications can advance periodontal therapy.
- Cell-based approaches represent a novel frontier in treating periodontitis.
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