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Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm

Marta Siergiejuk1, Marek Gacko, Anna Worowska

  • 1Department of Vascular Surgery and Transplantology, Medical University of Bialystok, Poland. martasiergiejuk1983@o2.pl

Folia Histochemica Et Cytobiologica
|April 29, 2011
PubMed

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z-Phe-Ala. It was lower on Z-Phe-Phe, Z-Glu-Tyr, Z-Glu-Phe, Z-Gly-Phe, and the lowest activity was on Z-Gly-Ala. We conclude that cathepsin A's activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity.

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