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Updated: Jun 2, 2026

Hemi-laryngeal Setup for Studying Vocal Fold Vibration in Three Dimensions
Published on: November 25, 2017
Morphological aspects of the euphonic voice
Bożena Kosztyła-Hojna1, Anna Andrzejewska, Diana Moskal
1Department of Clinical Phonoaudiology and Logopedics, Medical University of Bialystok, Poland. fono@umwb.edu.pl
Healthy vocal folds exhibit normal structure and function, crucial for producing a clear, euphonic voice. This study found no significant morphological changes in the vocal fold mucosa of individuals with healthy voices, indicating optimal physiological conditions.
Area of Science:
- Laryngology
- Voice Science
- Histopathology
Background:
- The quality of a euphonic voice depends on complex physiological interactions, with vocal fold vibration being paramount.
- The layered structure of the laryngeal mucosa is essential for the physiological motion of vocal folds.
Purpose of the Study:
- To assess the degree of dysphonia using the Union of European Phoniatrics (UEP) scale.
- To evaluate the morphology and ultramorphology of the vocal fold mucosa in individuals with euphonic voices.
Main Methods:
- Videoendoscopy (VLS) and videostroboscopy (VLSS) to visualize vocal fold vibration.
- Light and transmission electron microscopy of vocal fold mucosa samples (surgical and autopsy).
- Morphological assessment of the inter-membranous part of the vocal fold mucosa.
Main Results:
- Euphonia correlated with a 1° dysphonia (UEP) and physiological VLS/VLSS findings.
- No significant morphological or ultramorphological changes were observed in the epithelial cells, basal membrane, or stroma of healthy vocal folds.
- Specific cellular components like pericytes, basal membrane folds, and immune cells were noted in healthy vocal fold mucosa.
Conclusions:
- The vocal fold mucosa in individuals with euphonic voices demonstrates normal morphology and ultramorphology.
- Minor pathological changes (atrophy, polypoid degeneration) were infrequent in the studied population.
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