Related Experiment Video
Updated: Jun 2, 2026

Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock
Published on: October 28, 2022
How to use biomarkers efficiently in acute kidney injury
Norbert H Lameire1, Raymond C Vanholder, Wim A Van Biesen
1Renal Division, University Hospital, Ghent University, Ghent, Belgium. norbert.lameire@ugent.be
Abstract:
We discuss the performance of novel biomarkers in acute kidney injury (AKI). Comparison of the areas under the receiver operating characteristic curves of several biomarkers with some clinical and/or routine biochemical outcome parameters reveals that none of the biomarkers has demonstrated a clear additional value beyond the traditional approach in clinical decision making in patients with AKI. Unscrutinized use of these biomarkers may distract from adequate clinical evaluation and carries the risk of worse instead of better patient outcome.
Related Concept Videos
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury I: Introduction
Acute Kidney Injury V: Interprofessional Care
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury VI: Nursing Management
Acute Kidney Injury II: Pathophysiology

