Related Experiment Video
Updated: Jun 2, 2026

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
A family of multicyclic indolosesquiterpenes from a bacterial endophyte
Ling Ding1, Armin Maier, Heinz-Herbert Fiebig
1Leibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstr. 11a, D-07745, Jena, Germany.
Abstract:
Three novel indolosesquiterpenes, xiamycin B (1b), indosespene (2), and sespenine (3), along with the known xiamycin A (1a) were isolated from the culture broth of Streptomyces sp. HKI0595, a bacterial endophyte of the widespread mangrove tree Kandelia candel. Agar diffusion assays revealed moderate to strong antimicrobial activities against several bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis, while no cytotoxicity against human tumor cell lines was observed. Together with the previously reported oridamycin, the endophyte metabolites represent the first indolosesquiterpenes isolated from prokaryotes.
More Related Videos
Related Concept Videos
Bacterial Phylum Planctomycetes
Bacterial Phylum Tenericutes
Bacterial Phylum Actinobacteria
Bacterial Phylum Spirochaetes
Bacterial Phylum Firmicutes
Biosynthesis in Bacteria

