Related Experiment Videos
Human cells infected with retrovirus vectors acquire an endogenous murine provirus
D T Scadden1, B Fuller, J M Cunningham
1Howard Hughes Medical Institute, Boston, Massachusetts.
Journal of Virology
|January 1, 1990
Abstract:
A 5.2-kilobase mouse RNA is expressed in human cells following infection with recombinant retroviruses propagated in mouse NIH 3T3 cells as psi-2 pseudotypes. This RNA is transcribed from a defective mink cell focus-forming provirus and copackaged into virions and integrated into human target cell DNA at a frequency comparable to that of the recombinant retrovirus genome.