Mesenteric ischemia--a complex disease requiring an interdisciplinary approach. A review of the current literature

Anca Florian1, Ruxandra Jurcut, Ioana Lupescu

  • 1Cardiology Department, Prof. Dr. C.C. Iliescu Institute of Emergency for Cardiovascular Diseases, Bucharest, Romania.

Insights

Mesenteric ischemia, a reduction in intestinal blood flow, is increasingly diagnosed. Prompt restoration of blood flow is crucial for survival in this vascular emergency.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Emergency Medicine

Background:

  • Mesenteric ischemia results from reduced intestinal blood flow, leading to severe complications like sepsis, bowel infarction, and death.
  • The incidence of mesenteric ischemia is rising due to increased awareness, an aging population, and more critically ill patients.
  • Acute mesenteric ischemia is a vascular emergency with high mortality (60-80%), necessitating rapid diagnosis and intervention.

Purpose of the Study:

  • To review the causes, diagnosis, and treatment of acute and chronic mesenteric ischemia.
  • To emphasize the importance of early diagnosis and prompt revascularization in managing mesenteric ischemia.
  • To discuss current and emerging treatment modalities for mesenteric ischemia.

Main Methods:

  • Review of current literature on mesenteric ischemia.
  • Analysis of diagnostic criteria and clinical presentations.
  • Overview of treatment strategies, including medical, endovascular, and surgical options.

Main Results:

  • Early diagnosis of mesenteric ischemia relies on a high index of suspicion, compatible history, and physical examination.
  • Restoring intestinal blood flow quickly is the primary treatment goal for acute mesenteric ischemia.
  • Chronic mesenteric ischemia diagnosis involves clinical picture, splanchnic vessel occlusion, and exclusion of other causes.

Conclusions:

  • Prompt diagnosis and rapid restoration of intestinal blood flow are critical for improving outcomes in mesenteric ischemia.
  • Treatment options for mesenteric ischemia range from medical management to endovascular procedures and surgery.
  • Both acute and chronic mesenteric ischemia require timely intervention, with revascularization being a key therapeutic approach.

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