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Updated: Jun 2, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Mesenteric ischemia--a complex disease requiring an interdisciplinary approach. A review of the current literature
Anca Florian1, Ruxandra Jurcut, Ioana Lupescu
1Cardiology Department, Prof. Dr. C.C. Iliescu Institute of Emergency for Cardiovascular Diseases, Bucharest, Romania.
Abstract:
Mesenteric ischemia is caused by a reduction in intestinal blood flow with potential catastrophic clinical consequences: sepsis, bowel infarction, and death. In the recent years, the incidence of mesenteric ischemia increased, now accounting for 0.1% of hospital admissions. Among the multiple factors responsible for this change is the heightened awareness for the diagnoses, the advanced mean age of the population and the increasing number of critically ill patients. Acute mesenteric ischemia is a potentially fatal vascular emergency, with overall mortality of 60-80%; prompt diagnosis and treatment are paramount. A high index of suspicion in the setting of a compatible history and physical examination serves as the cornerstone to early diagnosis of mesenteric ischemia. Restoration of intestinal blood flow, as rapidly as possible, is the main goal of treatment in patients with acute mesenteric ischemia. This may be achieved by medical means, endovascular procedures and by surgery. Chronic mesenteric ischemia is an uncommon process that occurs only when severe atherosclerotic narrowing of a major splanchnic vessel exists in association with occlusion of one or two of the remaining vessels. Its diagnosis is mainly based on the characteristic clinical picture, on the presence of an occlusive lesion in the splanchnic vessels and on the absence of other common causes of abdominal pain. The means available for mesenteric revascularization are the surgical techniques of flow restoration and the more recently developed percutaneous transluminal procedures.
Insights
Mesenteric ischemia, a reduction in intestinal blood flow, is increasingly diagnosed. Prompt restoration of blood flow is crucial for survival in this vascular emergency.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Emergency Medicine
Background:
- Mesenteric ischemia results from reduced intestinal blood flow, leading to severe complications like sepsis, bowel infarction, and death.
- The incidence of mesenteric ischemia is rising due to increased awareness, an aging population, and more critically ill patients.
- Acute mesenteric ischemia is a vascular emergency with high mortality (60-80%), necessitating rapid diagnosis and intervention.
Purpose of the Study:
- To review the causes, diagnosis, and treatment of acute and chronic mesenteric ischemia.
- To emphasize the importance of early diagnosis and prompt revascularization in managing mesenteric ischemia.
- To discuss current and emerging treatment modalities for mesenteric ischemia.
Main Methods:
- Review of current literature on mesenteric ischemia.
- Analysis of diagnostic criteria and clinical presentations.
- Overview of treatment strategies, including medical, endovascular, and surgical options.
Main Results:
- Early diagnosis of mesenteric ischemia relies on a high index of suspicion, compatible history, and physical examination.
- Restoring intestinal blood flow quickly is the primary treatment goal for acute mesenteric ischemia.
- Chronic mesenteric ischemia diagnosis involves clinical picture, splanchnic vessel occlusion, and exclusion of other causes.
Conclusions:
- Prompt diagnosis and rapid restoration of intestinal blood flow are critical for improving outcomes in mesenteric ischemia.
- Treatment options for mesenteric ischemia range from medical management to endovascular procedures and surgery.
- Both acute and chronic mesenteric ischemia require timely intervention, with revascularization being a key therapeutic approach.
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