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Updated: May 10, 2026

Lung Tumor Cell Recruitment Assay
Published on: February 26, 2019
Does metabolite deficiency mark oncogenic cell cycles?
1University of Cambridge, Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, UK. arv22@hutchison-mrc.cam.ac.uk
Abstract:
Genome instability occurs early in the development of most cancers. Bester et al. now provide evidence that oncogenic signals trigger cell division without coordinate nucleotide synthesis, engendering aberrant DNA replication and damage that could promote carcinogenesis. A mismatch between proliferation and metabolite production may characterize oncogenic cell cycles.
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