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Comparison of polysaccharides from different Dendrobium using saccharide mapping.

J Xu¹, J Guan, X J Chen

¹State Key Laboratory for Quality Research in Chinese Medicine, and Institute of Chinese Medical Sciences, University of Macau, Macao SAR, PR China.

Journal of Pharmaceutical and Biomedical Analysis

|May 3, 2011

Summary

Polysaccharides from Dendrobium, a traditional Chinese herb, vary significantly between species and locations. Saccharide mapping reveals these differences, aiding in quality control for medicinal Dendrobium products.

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Area of Science:

Pharmacognosy
Phytochemistry
Traditional Chinese Medicine

Background:

Dendrobium species, known as Shihu, are extensively utilized in Traditional Chinese Medicine.
While small molecules in Dendrobium are well-studied, research on their polysaccharides remains limited.
Polysaccharides are recognized as significant bioactive components in Dendrobium.

Purpose of the Study:

To compare polysaccharides from various Dendrobium species and geographical origins.
To investigate the variability of Dendrobium polysaccharides using saccharide mapping.
To establish a method for controlling the quality of medicinal Dendrobium.

Main Methods:

Saccharide mapping was employed to analyze and compare polysaccharides.
Polysaccharides were extracted from different Dendrobium species and locations.

Main Results:

Significant variations in polysaccharide profiles were observed among different Dendrobium species and locations.
Despite variations, certain common characteristics were identified in Dendrobium polysaccharides.
Saccharide mapping effectively differentiated polysaccharide compositions.

Conclusions:

Dendrobium polysaccharides exhibit considerable diversity based on species and origin.
The observed variations in polysaccharides are crucial for Dendrobium quality control.
Saccharide mapping is a valuable tool for assessing Dendrobium quality and authenticity.