Related Experiment Video
Updated: Jun 2, 2026

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
Published on: May 26, 2023
Sepsis-associated takotsubo cardiomyopathy can be reversed with levosimendan
Marios Karvouniaris1, John Papanikolaou, Demosthenes Makris
1Critical Care Medicine Department, University Hospital of Larisa, Larissa 41000, Greece. markayvel@yahoo.gr
Abstract:
Sepsis is a stressful physical condition, and at the acute phase, overstimulation of the sympathetic nervous system may occur; these events have the potential to induce cardiomyopathy. Takotsubo cardiomyopathy (TTC) is a form of catecholamine-induced cardiomyopathy, which occurs very rarely in sepsis. However, TTC management in critically ill patients with sepsis may be challenging because the use of exogenous catecholamines for circulatory support might augment further TTC. Herein, we report a rare case of TTC after urosepsis; and we point out that cardiac function may improve after catecholamine withdrawal and the application of calcium channel sensitizer levosimendan.
Related Concept Videos
Myocarditis III: Medical Management
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy V: Interprofessional Care
Heart Failure Drugs: Inotropic Agents
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy VI: Nursing Management