Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Growth of Cartilage and Bone Tissue

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Establishment of a mathematical prediction model to evaluate the probability of malignancy or benign in patients with solitary pulmonary nodules].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences·2011

Same author

Surface substance loss of subsurface bovine enamel lesions after different steps of the resinous infiltration technique: a 3D topography analysis.

Odontology·2011

Same author

Expression of IL-23/Th17 pathway in a murine model of Coxsackie virus B3-induced viral myocarditis.

Virology journal·2011

Same author

Extracellular matrix peptides of Artemia cyst shell participate in protecting encysted embryos from extreme environments.

PloS one·2011

Same author

Therapeutic effect of carboxymethylated and quanternized chitosan on insulin resistance in high-fat-diet-induced rats and 3T3-L1 adipocytes.

Journal of biomaterials science. Polymer edition·2011

Same author

Role of reactive oxygen species in triptolide-induced apoptosis of renal tubular cells and renal injury in rats.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban·2011

Same journal

Microbial C1 assimilation pathways for chemical synthesis: from native metabolism to synthetic design.

Current opinion in biotechnology·2026

Same journal

Medicinal plants fermentation: current knowledge and perspectives.

Current opinion in biotechnology·2026

Same journal

Fermented foods: lessons learned from metagenomics.

Current opinion in biotechnology·2026

Same journal

Microfluidic platforms for the transient transfection of mammalian cells: recent developments and challenges.

Current opinion in biotechnology·2026

Same journal

Harvesting insights from recent advances in yeast genomics for predictable and precision wine fermentation.

Current opinion in biotechnology·2026

Same journal

Minimal enzyme cascades for the aromatic-to-aromatic upgrading of lignin monomers.

Current opinion in biotechnology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Published on: April 14, 2026

Recent progress in cartilage tissue engineering.

Michael Keeney¹, Janice H Lai, Fan Yang

¹Department of Orthopaedic Surgery, Stanford University, Stanford, CA 94305, USA.

Current Opinion in Biotechnology

|May 3, 2011

Summary

This summary is machine-generated.

Cartilage tissue engineering needs better therapies. This review explores new strategies using advanced scaffolds, cell sources, and in situ monitoring for functional cartilage regeneration.

More Related Videos

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

3D Magnetic Stem Cell Aggregation and Bioreactor Maturation for Cartilage Regeneration

3D Magnetic Stem Cell Aggregation and Bioreactor Maturation for Cartilage Regeneration

Published on: April 27, 2017

Related Experiment Videos

Last Updated: Jun 2, 2026

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Published on: April 14, 2026

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Published on: May 21, 2013

3D Magnetic Stem Cell Aggregation and Bioreactor Maturation for Cartilage Regeneration

3D Magnetic Stem Cell Aggregation and Bioreactor Maturation for Cartilage Regeneration

Published on: April 27, 2017

Area of Science:

Biomedical Engineering
Regenerative Medicine
Tissue Engineering

Background:

Cartilage tissue engineering has seen limited clinical translation despite extensive research.
Effective therapies for cartilage repair remain a significant unmet need.

Purpose of the Study:

To review recent advancements in cartilage tissue engineering strategies.
To highlight novel approaches for achieving long-term functional cartilage tissue.

Main Methods:

Focus on identifying suitable cell sources for cartilage regeneration.
Discusses the design of 3D scaffolds with dynamic and patterned cues.
Covers mimicking native tissue structure, host integration, and in situ monitoring.

Main Results:

Progress in developing sophisticated biomaterials and cell-based strategies.
Advancements in creating scaffolds that guide cell behavior and tissue development.
Improved methods for assessing tissue regeneration and cell fate in real-time.

Conclusions:

Novel strategies are emerging to overcome limitations in cartilage repair.
Integrating advanced scaffolds, cell sources, and monitoring techniques is key.
Future research aims to enhance long-term functionality and clinical applicability.