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Published on: March 30, 2018
Plasmablastic lymphoma clinically presenting in the urinary tract
Jean-Christophe Tille1, Marie-Françoise Pelte, Julien Schwartz
1Department of Genetics and Laboratory Medicine, Division of Clinical Pathology, University Hospital of Geneva, 1211 Geneva 4, Switzerland. jean-christophe.tille@hcuge.ch
Abstract:
Plasmablastic lymphoma is a high-grade B-cell lymphoma that poses major diagnostic problems and carries an extremely poor prognosis. This tumor was first described in the oral cavity of HIV+ patients but has since been identified in other sites and in seronegative patients. We describe 2 cases of plasmablastic lymphoma of the urinary tract that both presented with hydronephrosis. One occurred in an HIV+ patient and harbored a MYC translocation; the other, in an HIV- patient with no translocation detected.
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