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Published on: February 10, 2023
Upper-extremity deep venous thrombosis: a review
1University of South Florida, Tampa, FL, USA. cmai@health.usf.edu
Insights
Upper-extremity deep venous thrombosis (UEDVT) is less common but increasingly prevalent, especially in complex patients. This review clarifies UEDVT diagnosis, risk factors, and evidence-based treatment strategies.
Area of Science:
- Vascular Medicine
- Hematology
- Clinical Thrombosis
Background:
- Upper-extremity deep venous thrombosis (UEDVT) is less common than lower-extremity DVT.
- UEDVT incidence is rising in patients with central venous catheters and complex medical conditions.
- Despite similar adverse outcomes to lower-extremity DVT, UEDVT requires specific diagnostic and management considerations.
Purpose of the Study:
- To differentiate primary and secondary UEDVT.
- To assess risk factors and clinical sequelae of UEDVT, comparing them to lower-extremity DVT.
- To outline evidence-based treatment and prevention strategies for secondary UEDVT.
Main Methods:
- Literature review of existing studies on upper-extremity deep venous thrombosis.
- Comparative analysis of UEDVT versus lower-extremity deep venous thrombosis.
- Synthesis of clinical evidence for diagnostic and therapeutic approaches.
Main Results:
- UEDVT shares adverse consequences with lower-extremity DVT.
- Central venous catheters are a significant risk factor for secondary UEDVT.
- Emerging evidence refines the understanding of UEDVT prognosis and management.
Conclusions:
- Physicians need to be aware of UEDVT's unique diagnostic and treatment considerations.
- Management strategies for UEDVT are evolving and require clinical familiarity.
- Differentiating UEDVT types and understanding risk factors are key for effective patient care.
Abstract:
Upper-extremity deep venous thrombosis is less common than lower-extremity deep venous thrombosis. However, upper-extremity deep venous thrombosis is associated with similar adverse consequences and is becoming more common in patients with complex medical conditions requiring central venous catheters or wires. Although guidelines suggest that this disorder be managed using approaches similar to those for lower-extremity deep venous thrombosis, studies are refining the prognosis and management of upper-extremity deep venous thrombosis. Physicians should be familiar with the diagnostic and treatment considerations for this disease. This review will differentiate between primary and secondary upper-extremity deep venous thromboses; assess the risk factors and clinical sequelae associated with upper-extremity deep venous thrombosis, comparing these with lower-extremity deep venous thrombosis; and describe an approach to treatment and prevention of secondary upper-extremity deep venous thrombosis based on clinical evidence.
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