Intoxications amenable to extracorporeal removal
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Updated: Jun 2, 2026

In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
Published on: November 10, 2011
James F Winchester1, Nikolas B Harbord
1Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY 10003, USA. jwinches@bethisraelny.org
Abstract:
Extracorporeal removal of drugs was first attempted in 1913, by John Jacob Abel. Previously known to be a rarity, dialysis and to a lesser extent hemoperfusion have now become obvious tools for nephrologists in treating life-threatening cases of poisoning. Moreover, for dialysis patients, dialysis along with chelation therapy for removal of aluminum, once known to be common in the United States, is resurging in some countries. This article will discuss the principles of drug removal, the indications for dialysis, and give a brief outline of poisons amenable to dialysis.
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