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Giant tricholemmal squamous cell carcinoma with cranial infiltration
Summary
Giant tricholemmal squamous cell carcinoma, a rare scalp cancer, invaded the skull in a 67-year-old man. Treatment focused on tumor reduction and wound closure due to incurable advanced cancer.
Area of Science:
- Dermatology
- Oncology
- Surgical Pathology
Background:
- Tricholemmal squamous cell carcinoma (TSC) is a rare variant of squamous cell carcinoma.
- It is generally considered to have a more benign clinical course compared to conventional squamous cell carcinoma.
- This case highlights a rare aggressive presentation of TSC.
Observation:
- A 67-year-old male presented with a giant tricholemmal squamous cell carcinoma on the scalp.
- Radiological investigations revealed extensive skull destruction and intracranial invasion by the tumor.
- The advanced nature of the tumor precluded curative treatment options.
Findings:
- Surgical debulking of the tumor mass was performed to manage the advanced disease.
- Wound closure was achieved using a sandwich split-thickness skin mesh graft with a dermal template.
- The case underscores the potential for aggressive behavior in TSC despite its typical benign classification.
Implications:
- This case emphasizes the importance of thorough evaluation for advanced squamous cell carcinoma on the scalp, including cranial invasion.
- Management strategies for extensive scalp tumors may involve palliative debulking and reconstructive surgery.
- Further research into the factors influencing the aggressive behavior of tricholemmal squamous cell carcinoma is warranted.
