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Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
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Survival with treated and well-controlled blood pressure: findings from a prospective cohort study

Debbie A Lawlor1, Lois Kim, Richard Morris

  • 1MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom. d.a.lawlor@bristol.ac.uk

Plos One
|May 3, 2011
PubMed

Insights

Half of older adults have untreated hypertension, increasing their risk of cardiovascular disease. Even treated hypertension poses risks if not well-controlled, highlighting the need for better management strategies to prevent heart disease.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Hypertension is a major risk factor for cardiovascular disease (CVD).
  • Effective blood pressure management is crucial for reducing CVD incidence.
  • Prevalence and control of hypertension in older adults require further investigation.

Purpose of the Study:

  • To compare survival and incident CVD among different hypertension control groups.
  • To assess risks associated with untreated, poorly controlled, and well-controlled hypertension.
  • To evaluate CVD outcomes in older adults based on their hypertension status.

Main Methods:

  • Utilized data from the British Regional Heart Study and British Women's Heart and Health Study (N=6476).
  • Assessed blood pressure and treatment status at baseline (1998-2001) in adults aged 60-79.
  • Followed participants for a median of 8 years, tracking mortality and non-fatal CVD events.

Main Results:

  • Nearly half of participants had untreated hypertension (52% women, 49% men).
  • Poorly controlled (22% women, 18% men) and untreated hypertension significantly increased CVD risk.
  • Well-controlled hypertension also showed an increased CVD risk (HR 1.38), though less pronounced after adjustments.

Conclusions:

  • A high prevalence of untreated hypertension exists in older British adults.
  • Inadequate control of treated hypertension contributes to elevated cardiovascular disease risk.
  • Hypertension, regardless of treatment status, is linked to increased CVD risk compared to normotensive individuals.
Abstract

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