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Related Concept Videos

Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

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Related Experiment Video

Updated: Jun 2, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
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Published on: May 31, 2024

[Post-infectious irritable bowel syndrome].

F Pallotti1, E Fogacci, C Frisoni

  • 1Dipartimento di Medicina Clinica, Università di Bologna, Italy.

La Clinica Terapeutica
|May 3, 2011
PubMed
Summary
This summary is machine-generated.

Acute infectious gastroenteritis is a major risk factor for developing irritable bowel syndrome (IBS). Understanding post-infectious IBS (PI-IBS) risk factors and potential prevention is crucial for managing this common disorder.

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Chronic Salmonella Infection Induced Intestinal Fibrosis
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Area of Science:

  • Gastroenterology
  • Microbiology
  • Immunology

Context:

  • Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder.
  • Acute infectious gastroenteritis is the most significant identified risk factor for IBS development.
  • Limited data exists on the incidence and prevalence of post-infectious IBS (PI-IBS).

Purpose:

  • To review the current understanding of post-infectious IBS (PI-IBS).
  • To identify risk factors associated with PI-IBS development.
  • To explore potential preventive strategies and future research directions.

Summary:

  • Pathogen virulence, younger age, female sex, prolonged illness, and psychological disturbances are key risk factors for PI-IBS.
  • Low-grade mucosal inflammation and alterations in gut microbiota are implicated in PI-IBS pathogenesis.
  • Probiotics and non-absorbable antibiotics during acute infection may offer preventive benefits.

Impact:

  • Highlights the link between infections and functional gastrointestinal disorders like IBS.
  • Emphasizes the need for further research into PI-IBS etiology and targeted therapies.
  • Suggests potential preventive interventions for individuals at risk of PI-IBS.