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Hepatitis A seroprevalence among infants aged 12 months in Ankara

Osman Tolga Ince1, S Songül Yalçin, Kadriye Yurdakök

  • 1Division of Social Pediatrics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

The Turkish Journal of Pediatrics
|May 4, 2011
PubMed

Insights

Hepatitis A seroprevalence in Ankara infants was 23.5%. Understanding maternal antibody decay is crucial for optimal infant hepatitis A vaccination timing in Turkey.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Immunology

Background:

  • Hepatitis A seroprevalence studies inform infection understanding and vaccination response.
  • Maternal antibodies can impact infant immune responses to hepatitis A vaccination.
  • Optimal infant vaccination timing requires knowledge of maternal antibody decay.

Purpose of the Study:

  • To determine hepatitis A seroprevalence in 12-month-old infants in Ankara.
  • To assess gender-based differences in hepatitis A seropositivity among infants.
  • To inform hepatitis A vaccination strategies in Turkey.

Main Methods:

  • A cross-sectional study was conducted.
  • 601 healthy infants aged 12 months in Ankara were enrolled.
  • Hepatitis A seropositivity was assessed.

Main Results:

  • Overall hepatitis A seropositivity was 23.5% among the infants.
  • No significant gender difference in seropositivity was observed (22.6% males, 24.5% females).

Conclusions:

  • Hepatitis A infection is prevalent in young children in Ankara.
  • Further seroprevalence studies across different age groups are needed.
  • Optimal hepatitis A vaccination strategies require more data on maternal antibody decay and infant seroprevalence.

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