Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Group Design02:01

Group Design

The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between the two are due to...
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs01:20

Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs

Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to subjects...
Crossover Experiments01:16

Crossover Experiments

Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs01:15

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
Censoring Survival Data01:09

Censoring Survival Data

Survival analysis is a statistical method used to analyze time-to-event data, often employed in fields such as medicine, engineering, and social sciences. One of the key challenges in survival analysis is dealing with incomplete data, a phenomenon known as "censoring." Censoring occurs when the event of interest (such as death, relapse, or system failure) has not occurred for some individuals by the end of the study period or is otherwise unobservable, and it might have many different reasons...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A causal framework for explaining effect heterogeneity in conceptual replications.

Psychological methods·2026
Same author

Drawing credible directed acyclic graphs for causal inference.

Psychological methods·2026
Same author

A new four-arm within-study comparison: Design, implementation, and data.

Observational studies·2026
Same author

Clinical Impact of Continuous Glucose Monitoring in Noninsulin Treated Type 2 Diabetes: A Review.

Diabetes technology & therapeutics·2026
Same author

Clinical Risk Factors for Stroke and Associations with Microembolic Signals on Transcranial Doppler.

Journal for vascular ultrasound : JVU·2025
Same author

Training the Next Generation of Data Monitoring Committee Members: An Initiative of the Heart Failure Collaboratory.

JACC. Heart failure·2024
Same journal

Bayesian evaluation for latent variable models: A tutorial on computing information criteria and bayes factors with the r package bleval.

Psychological methods·2026
Same journal

A stochastic block prior for clustering in graphical models.

Psychological methods·2026
Same journal

Three-level vector autoregressive models.

Psychological methods·2026
Same journal

Scaling cognitive modeling to big data: A deep learning approach to studying individual differences in evidence accumulation model parameters.

Psychological methods·2026
Same journal

Best practices in multilevel modeling for within-cluster group comparisons: An evaluation of coding strategies reflecting group composition and heterogeneity.

Psychological methods·2026
Same journal

A unified framework for psychometrics in experimental psychology: The standardized generalized hierarchical factor model.

Psychological methods·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

RBDT: A Computerized Task System based in Transposition for the Continuous Analysis of Relational Behavior Dynamics in Humans
11:09

RBDT: A Computerized Task System based in Transposition for the Continuous Analysis of Relational Behavior Dynamics in Humans

Published on: July 17, 2021

A randomized experiment comparing random and cutoff-based assignment.

William R Shadish1, Rodolfo Galindo, Vivian C Wong

  • 1School of Social Sciences, Humanities, and Arts, University of California, Merced, 5200 North Lake Road, Merced, CA 95343, USA. wshadish@ucmerced.edu

Psychological Methods
|May 4, 2011
PubMed
Summary
This summary is machine-generated.

This study compares randomized experiments and regression discontinuity designs, finding they yield similar results when applied identically. Careful parameter estimation is crucial for accurate comparisons between these causal inference methods.

More Related Videos

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
13:20

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance

Published on: December 5, 2025

Related Experiment Videos

Last Updated: Jun 2, 2026

RBDT: A Computerized Task System based in Transposition for the Continuous Analysis of Relational Behavior Dynamics in Humans
11:09

RBDT: A Computerized Task System based in Transposition for the Continuous Analysis of Relational Behavior Dynamics in Humans

Published on: July 17, 2021

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
13:20

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance

Published on: December 5, 2025

Area of Science:

  • Econometrics
  • Causal Inference
  • Experimental Design

Background:

  • Randomized experiments are the gold standard for causal inference.
  • Regression discontinuity designs offer an alternative when randomization is not feasible.
  • Previous comparisons have shown mixed results due to methodological differences.

Purpose of the Study:

  • To directly compare randomized experiments and regression discontinuity designs under controlled conditions.
  • To investigate the impact of parameter estimation on the agreement between the two methods.
  • To assess the validity of regression discontinuity designs as an alternative to randomized experiments.

Main Methods:

  • Randomly assigned 588 participants to either a randomized experiment or a regression discontinuity design.
  • Ensured participants were treated identically across both designs.
  • Employed parametric, semiparametric, and nonparametric methods to model nonlinearities.
  • Compared estimates for both identical and different parameters.

Main Results:

  • Estimates from regression discontinuity designs closely approximated those from randomized experiments.
  • Significant exceptions were observed, highlighting the importance of parameter definition.
  • The choice of modeling approach (parametric, semiparametric, nonparametric) influenced the results.
  • The study identified challenges in defining "agreement" between the two estimation methods.

Conclusions:

  • Regression discontinuity designs provide a reliable approximation of randomized experiment results when implemented carefully.
  • Methodological rigor, particularly in parameter estimation and nonlinearity modeling, is essential for valid comparisons.
  • Further research is needed to establish clear criteria for assessing the concordance between these causal inference techniques.