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Correlation between koilocytes and human papillomavirus detection by PCR in oral and oropharynx squamous cell

Glauco Issamu Miyahara1, Luciana Estevam Simonato, Neivio José Mattar

  • 1Departamento de Patologia e Propedêutica, Universidade Estadual Paulista, Araçatuba, SP, Brasil. miyahara@foa.unesp.br

Memorias Do Instituto Oswaldo Cruz
|May 4, 2011
PubMed

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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...