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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Muscles of the Anterior Neck01:26

Muscles of the Anterior Neck

The anterior neck muscles are the group of muscles covering the front part of the neck. These muscles are classified into three subgroups. The first one is the superficial muscles, the most visible muscles in the front of the neck. It includes the platysma and sternocleidomastoid. The second group is the suprahyoid muscles, located above the hyoid bone. This group comprises the digastric, mylohyoid, geniohyoid, and stylohyoid. Lastly, the infrahyoid muscles are found below the hyoid bone and...

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Related Experiment Video

Updated: Jun 2, 2026

Modified Radical Neck Dissection for Cervical Metastasis
06:05

Modified Radical Neck Dissection for Cervical Metastasis

Published on: February 20, 2026

[Neck skin collision tumor].

Helma Maria Chedid1, Aglailton Dos Santos Menezes, Kiyoshi Fernandes Aikawa

  • 1Departamento de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia, Hospital Heliópolis, São Paulo, SP, BR.

Revista Do Colegio Brasileiro De Cirurgioes
|May 4, 2011
PubMed
Summary

Collision tumors, a mix of basal cell carcinoma and squamous cell carcinoma, are aggressive skin cancers. Surgical resection is the primary treatment, but high local recurrence rates impact survival.

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Modified Radical Neck Dissection for Cervical Metastasis
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Collision tumors, a rare malignant neoplasm of the skin, arise from the coexistence of basal cell carcinoma and squamous cell carcinoma.
  • These tumors are associated with sun exposure and predominantly affect light-skinned men in their fifth or sixth decades.

Observation:

  • A case report details a 73-year-old male patient with two progressively growing cervical lesions.
  • Histological examination confirmed the presence of squamous cell carcinoma adjacent to basal cell carcinoma, with a distinct interface.

Findings:

  • Collision tumors exhibit unique clinical behavior and histological characteristics, differing from individual basal cell carcinoma or squamous cell carcinoma.
  • Local recurrence rates range from 12% to 45%, with regional recurrence around 7.5%.

Implications:

  • Accurate histological diagnosis is crucial for differentiating collision tumors from other skin malignancies.
  • Surgical resection is the primary treatment; however, local recurrence remains a significant challenge to disease-free survival, necessitating further research into management strategies.