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Updated: Jun 2, 2026
04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
[Neonatal dengue in Peru: a case report]
Hermann Silva Delgado1, Juan Carlo Ruiz Ríos, Erick Leray Vela Barbarán
1Servicio de Neonatología, Hospital Apoyo Iquitos. silvahermann@hotmail.com
Summary
A newborn in Peru developed severe dengue symptoms, including fever and jaundice, after her mother died from the same illness. The infant recovered with supportive care, marking the first reported neonatal dengue case in Peru.
Area of Science:
- Virology
- Neonatal Medicine
- Infectious Diseases
Background:
- Severe dengue in mothers can pose risks to newborns.
- Vertical transmission of dengue virus is a potential concern.
Observation:
- A full-term female infant's mother died from severe dengue (multi-organ failure).
- The newborn presented with fever, jaundice, plasma leakage, thrombocytopenia, and hepatomegaly on day four of life.
Findings:
- The infant was diagnosed with dengue virus serotype 2 infection via RT-PCR.
- This case represents the first documented instance of neonatal dengue in Peru.
Implications:
- Highlights the risk of severe dengue in neonates born to infected mothers.
- Emphasizes the need for vigilant monitoring and supportive care for infants exposed to dengue.
- Underscores the importance of understanding dengue transmission dynamics in maternal-neonatal pairs.
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