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T-cell lymphosarcoma in a female African green monkey (Cercopithecus aethiops)
M J Jayo1, K Laber-Laird, B C Bullock
1Department of Comparative Medicine, Bowman Gray School of Medicine, Wake Forrest University, Winston-Salem, NC 27103.
Summary
A spontaneous lymphosarcoma in an African green monkey mimicked human T-lymphotropic virus type I-associated lymphoma. This simian T-lymphotropic virus (STLV) positive monkey
Area of Science:
- Veterinary Pathology
- Primate Oncology
- Viral Oncogenesis
Background:
- Malignant lymphoma in humans is often associated with human T-lymphotropic virus type I (HTLV-I).
- Simian T-lymphotropic virus (STLV) is the counterpart of HTLV-I in non-human primates.
- Spontaneous lymphoproliferative diseases in non-human primates can serve as models for human diseases.