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Underwear: contamination by human papillomaviruses.
C Bergeron1, A Ferenczy, R Richart
1Department of Pathology, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada.
American Journal of Obstetrics and Gynecology
|January 1, 1990
Summary
Human papillomavirus (HPV) DNA was detected in most genital lesions and some underwear samples. Positive underwear swabs correlated with significantly higher HPV recurrence rates.
Area of Science:
- Gynecologic Oncology
- Infectious Diseases
- Molecular Virology
Background:
- Genital human papillomavirus (HPV) infections are common and can lead to various lesions.
- Understanding transmission routes and recurrence factors is crucial for patient management.
Purpose of the Study:
- To investigate the presence of HPV DNA in genital lesions and on underwear cellular samples.
- To determine the correlation between HPV detection on underwear and lesion recurrence.
Main Methods:
- Filter hybridization technique (ViraPap-ViraType) was used to detect HPV DNA.
- Samples were analyzed from 74 patients with genital HPV-related lesions and their underwear swabs.
Main Results:
- HPV DNA was identified in 72% of lesional tissues (54/74 patients).
- HPV DNA was detected in 17% of underwear swabs (13/74 patients).
- Patients with positive underwear swabs had a 61% recurrence rate, compared to 29% in those with negative swabs (p < 0.05).
Conclusions:
- HPV DNA can be present on underwear worn by patients with genital lesions.
- Detection of HPV DNA on underwear is associated with a significantly higher risk of lesion recurrence.
- Underwear contamination may play a role in HPV persistence and disease recurrence.