Related Experiment Video
Updated: Jun 2, 2026

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
Published on: June 14, 2016
Virus-negative active lymphocytic myocarditis progressing to a fibrotic stage
Edouard Gerbaud1, Anne Vital, Matthew Erickson
1Soins Intensifs Cardiologiques-Plateau de Cardiologie Interventionnelle, CHU de Bordeaux, 5 Avenue de Magellan, 33604 Pessac, France.
This study details a rare case of lymphocytic myocarditis advancing to fibrosis, visualized with advanced imaging and confirmed by biopsy. The findings highlight an unusual diagnosis with a likely poor outlook.
Area of Science:
- Cardiology
- Pathology
- Medical Imaging
Background:
- Lymphocytic myocarditis is an inflammatory condition of the heart muscle.
- Progression to myocardial fibrosis can significantly impair cardiac function.
- Early and accurate diagnosis is crucial for patient management.
Observation:
- A unique case of lymphocytic myocarditis was observed.
- The condition progressed to a significant fibrotic stage.
- The progression was documented using advanced imaging techniques.
Findings:
- Multimodality imaging revealed characteristic features of myocardial fibrosis.
- Histopathological examination confirmed the diagnosis and fibrotic changes.
- The case highlights an uncommon presentation and progression pathway.
Implications:
- This case underscores the importance of multimodality imaging in diagnosing and staging myocarditis.
- Understanding the progression to fibrosis is key for predicting patient prognosis.
- Further research into fibrotic myocarditis may improve therapeutic strategies.
Related Concept Videos
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Rheumatic Heart Disease I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy
