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The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
A new case of spontaneous regression of inflammatory hepatic pseudotumor
Hichem Jerraya1, Slim Jarboui, Hassen Daghmoura
1Charles Nicolle's Hospital, Surgical Unit A, Tunis, Tunisia.
Abstract:
Introduction. Inflammatory pseudo-tumors (IPT) of the liver are rare and difficult to diagnose, because mimicking malignant tumors. Aim. We report a case of IPT of the liver wich diagnosis was made on clinical, radiological and evolutif features. Observation. A 15-year-old man had a 4-month history of abdominal pain in the right upper quadrant with fever and cought. Two successives ultrasonographies revealed a hypoechoic lesion occuping the segment VIII with 8 cm of diametre. Physical examination was normal. Laboratory investigation showed normal blood counts, liver function test and tumoral markers. Another ultrasonography was interpretated as normal. Tomodensitometry had showon a 3-cm lesion wich enhanced later after contrast injection. A second tomodensitometry done one mounth later described a 2-cm sub capsular heaptic lesion. Discussion. On routine activiy, pre operative diagnosis of IPT of the liver is difficut, and rarely made with certitude because mimicking a malignant tumor. In our cae report here, the analysis of previous history, of clinical, biological and radiological presentation, had permittes us to pose the diagnosis of PTI of the liver and this despite the absence of histological confirmation by percutaneous biopsy.
Insights
Inflammatory pseudo-tumors (IPT) of the liver are rare and mimic malignant tumors. Diagnosis relies on clinical, radiological, and evolutionary features, not just initial biopsies.
Area of Science:
- Hepatology
- Radiology
- Oncology
Background:
- Inflammatory pseudo-tumors (IPT) of the liver are uncommon hepatic lesions.
- Their presentation often mimics malignant liver tumors, complicating diagnosis.
- Early and accurate diagnosis is crucial for appropriate patient management.
Observation:
- A 15-year-old male presented with a 4-month history of right upper quadrant abdominal pain, fever, and cough.
- Initial ultrasonography revealed an 8 cm hypoechoic lesion in hepatic segment VIII.
- Subsequent imaging, including CT scans, showed evolving lesions of varying sizes (3 cm and 2 cm).
Findings:
- Laboratory investigations, including liver function tests and tumor markers, were within normal limits.
- Despite initial imaging challenges, clinical and radiological features suggested IPT.
- The diagnosis was established based on a comprehensive evaluation of clinical, biological, and radiological data.
Implications:
- This case highlights the diagnostic challenges posed by hepatic IPT.
- It underscores the importance of considering IPT in the differential diagnosis of liver lesions, even with atypical presentations.
- The study emphasizes the value of integrating clinical, radiological, and evolutionary data for non-invasive diagnosis of IPT.
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