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Multicentric malignant fibrous histiocytoma of soft tissue
H K Wolf1, J M Harrelson, E H Bossen
1Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710.
Abstract:
We present an unusual case of multicentric malignant fibrous histiocytoma of soft tissue. Over the past 24 years, a 67-year-old woman developed malignant fibrous histiocytoma in four different soft-tissue sites. There were two local recurrences of one of the tumors. Currently, there is no evidence of visceral involvement. The evidence suggests that this patient has a predisposition of the connective tissue to develop malignant tumors of fibrohistiocytic differentiation.

