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Is vitamin D status known among children living in Northern Italy?
Giuseppina Marrone1, Ilaria Rosso, Raffaella Moretti
1Department of Pediatrics, Udine Hospital, Piazzale S. Maria della Misericordia 15, Udine, Italy. pinamarrone@yahoo.it
Insights
Vitamin D deficiency is prevalent in children in northeastern Italy, with over half showing insufficient levels. Risk factors include winter, non-Caucasian ethnicity, and obesity, highlighting the need for targeted screening and education.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Vitamin D is crucial for bone health and immune function in children.
- Low vitamin D levels are a growing global concern, particularly in certain populations.
- Geographic location and lifestyle factors can significantly impact vitamin D status.
Purpose of the Study:
- To determine the prevalence of vitamin D deficiency in children aged 2-220 months in northeastern Italy.
- To identify risk factors associated with vitamin D deficiency in this pediatric cohort.
- To inform public health strategies for improving vitamin D status in at-risk children.
Main Methods:
- Serum 25-hydroxyvitamin D (25OHD) levels were measured in 93 children attending a pediatric clinic in Udine.
- Vitamin D status was categorized using established clinical definitions (severe deficiency, deficiency, insufficiency, sufficiency).
- Potential risk factors including age, ethnicity, season of blood draw, and obesity were investigated.
Main Results:
- A significant proportion of children (54.8%) exhibited insufficient or deficient vitamin D levels (25OHD < 50 nmol/l).
- Non-Caucasian children (75% insufficient) and obese children (90% deficient) showed significantly higher risks of vitamin D deficiency.
- Blood samples drawn during winter months (November-May) were associated with a higher prevalence of insufficient vitamin D (70.5%).
Conclusions:
- Vitamin D deficiency is a common health issue among children in northeastern Italy.
- Winter season, non-Caucasian ethnicity, and obesity are identified as key risk factors for vitamin D deficiency.
- Targeted screening and public health interventions focusing on sunlight exposure are recommended for high-risk pediatric groups.
Purpose:
To assess vitamin D status in children aged 2-220 months in northeastern Italy (latitude 46°). Serum 25-hydroxyvitamin D (25OHD) concentration was assessed in 93 children afferent to the Pediatric Department of the Hospital of Udine.
Methods:
Vitamin D status was defined as follows: sufficient with serum 25OHD between 50 and 250 nmol/l (level 4); insufficient between 37.5 and 50 nmol/l (level 3); deficient less than 37.5 nmol/l (level 2); severely deficient if less than 12.5 nmol/l (level 1). We investigated the potential risk factors of vitamin D deficit.
Results:
We found that six children (6.4%) had level 1, 36 (38.7%) had level 2, 9 (9.7%) had level 3, and only 45.2% had sufficient level of 25OHD. Immigrate children had a higher risk for vitamin D deficiency if compared with Italians: 75% of non-Italian children had an insufficient 25OHD level compared with 47.0% of Italian children (p = 0.0036). There was a marked seasonal effect on 25OHD level: when plasma sample was withdrawn between November and May, only 29.4% of children showed sufficient vitamin D level, while 70.5% was insufficient (p < 0.0001). Among the obese children, 9.0% had sufficient level of 25OHD with 90% being deficient (p = 0.01). We did not find any significant difference in vitamin D status among children in different age groups.
Conclusion:
Vitamin D deficiency is common in children living in northeastern Italy. The risk factors were winter season for blood withdrawal, non-Caucasian race, and obesity. These high-risk groups should be targeted for screening and educated about the need of sunlight exposure.
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