Vitamin D levels in Swiss multiple sclerosis patients
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Published on: December 9, 2015
Murat Yildiz1, Barbara Tettenborn, Norman Putzki
1Department of Neurology, Multiple Sclerosis Outpatient Clinic, Cantonal Hospital St. Gallen, Rorschacher Strasse 95, 9000 St. Gallen, Szitzerland. yildizmur@yahoo.com
Background:
Vitamin D levels have not been previously published for Swiss multiple sclerosis (MS) patients. An association between vitamin D status and disease activity in MS has been suggested.
Aim:
To define 25-hydroxy-vitamin D (25(OH)D) levels in Swiss multiple sclerosis patients.
Method:
Cross sectional case control study.
Results:
25(OH)D levels of 80 patients (76.3% female, mean age 37.9 ± 10.6 years, mean Expanded Disability Status Scale (EDSS) 2.6 ± 1.2) were collected. Mean levels of 25(OH)D were 57.0 ± 29.7 nmol/l (range 18-175 nmol/l) in all patients. A total of 21.3% of patients had levels ≤37 nmol/l and 75% had levels ≤70 nmol/l. 25(OH)D levels in patients with previous high disease activity were 52.8 ± 23.1 nmol/l versus 58.9 ± 32.3 nmol/l in the low disease activity group (p = 0.4).
Conclusion:
The prevalence of 25(OH)D deficiency was high in Swiss MS patients.
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