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Updated: Jun 2, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
The Novalung interventional lung assist as bridge to lung transplantation for self-ventilating patients - initial
Waldemar Bartosik1, Jim J Egan, Alfred E Wood
1Irish Heart and Lung Transplant Programme, Mater Misericordiae University Hospital, Eccles Street, Dublin, Ireland. w_bartosik@o2.pl
Abstract:
We report the use of the Novalung pumpless device in self-ventilating patients awaiting a lung transplantation. Two patients developed carbon dioxide retention with respiratory acidosis that did not respond to maximum medical therapy. The Novalung interventional lung assist was established as a bridge to lung transplantation. The first patient was successfully transplanted after 140 days, and this is the longest support that has been reported so far. The second patient was weaned off the Novalung after a short period. The Novalung is a valuable device for self-ventilating patients with carbon dioxide retention being bridged to lung transplantation.
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