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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...
Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment

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Related Experiment Video

Updated: Jun 2, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

[Smokers develop a nasal obstruction in supine position].

H Gudziol1, J Krause, M Stadeler

  • 1Uniklinikum, HNO-Klinik, Jena. hilmar.gudziol@med.uni-jena.de

Laryngo- Rhino- Otologie
|May 6, 2011
PubMed
Summary

Smokers experience nasal obstruction when lying down, confirmed by acoustic rhinometry. This nasal congestion resolves with physical activity, suggesting lifestyle changes can improve breathing.

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Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface
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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
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Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
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Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface
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Published on: October 8, 2013

Area of Science:

  • Otolaryngology
  • Respiratory Physiology
  • Cardiovascular Physiology

Context:

  • Previous studies indicate non-smokers do not develop nasal obstruction in a supine position.
  • Smokers exhibit different nasal respiratory behaviors compared to non-smokers.

Purpose:

  • To investigate nasal respiratory changes in smokers while in a supine position.
  • To assess the impact of physical activity on nasal respiration and cardiovascular parameters in smokers.

Summary:

  • Acoustic rhinometry revealed a significant decrease in total nasal volume in smokers when lying down, indicating nasal obstruction.
  • Approximately one-third of smokers reported noticeable nasal obstruction in the supine position.
  • Physical activity, such as climbing stairs, led to increased nasal parameters, blood pressure, and heart rate, with most parameters returning to baseline within minutes.

Impact:

  • Demonstrates cigarette smoke-induced nasal obstruction in smokers using acoustic rhinometry.
  • Highlights the potential benefit of elevating the head of the bed for smokers experiencing nasal obstruction.
  • Recommends topical corticosteroids for chronic rhinitis and smoking cessation as long-term solutions for improved nasal breathing.