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Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells

Xiaolei Ding1, Qiong Lin, Roberto Ensenat-Waser

  • 1Department of Cell Biology, Institute for Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.

Stem Cells and Development
|May 7, 2011
PubMed
Summary

Bmi1 (B-cell-specific Moloney murine leukemia virus integration site 1) enhances hematopoietic stem cell development from mouse embryonic stem cells. Forced Bmi1 expression promotes differentiation and expansion of hematopoietic progenitor cells.

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