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Updated: Jun 2, 2026

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
GlaxoSmithKline's experience of incurred sample reanalysis for dried blood spot samples
Matthew Barfield1, Sheelan Ahmad, Maria Busz
1Platform Technology & Science, Drug Metabolism & Pharmacokinetics, Worldwide Bioanalysis & Systems Management, GlaxoSmithKline Pharmaceuticals, Park Road, Ware, Hertfordshire, UK. matthew.barfield@gsk.com
Abstract:
Dried blood spots are becoming a popular alternative to plasma for many different applications. This has been driven by animal ethics but also by ease of use and cost savings. Recent regulatory guidance now has a requirement for incurred sample reanalysis. This article details three examples of incurred sample reanalysis using dried blood spot samples.

