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Related Concept Videos

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Related Experiment Video

Updated: Jun 2, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

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Published on: February 16, 2016

Isolated left ventricular noncompaction mimicking ventricular mass.

Praveen Jayan1, Ravindranath K Shankarappa, Rajiv Ananthakrishna

  • 1Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India. praveenjayan30@gmail.com

Echocardiography (Mount Kisco, N.Y.)
|May 7, 2011
PubMed
Summary
This summary is machine-generated.

Isolated left ventricular noncompaction, an inherited cardiomyopathy, is often missed by standard echocardiography. Contrast echocardiography is crucial for diagnosing this condition, especially when the left ventricular apex is involved.

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Last Updated: Jun 2, 2026

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Published on: February 16, 2016

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Published on: October 28, 2020

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Genetics

Background:

  • Isolated left ventricular noncompaction is a rare genetic cardiomyopathy.
  • It presents with excessive trabeculations and deep recesses in the left ventricle.
  • Diagnosis can be challenging due to limitations in imaging the left ventricular apex.

Observation:

  • Conventional 2D echocardiography failed to detect prominent trabeculations in a patient.
  • The left ventricular apex, a common site for noncompaction, was difficult to assess.
  • Contrast echocardiography was employed to overcome imaging limitations.

Findings:

  • Contrast echocardiography successfully identified multiple prominent trabeculations and deep intertrabecular recesses.
  • This confirmed the diagnosis of isolated left ventricular noncompaction.
  • The study highlights the diagnostic utility of contrast echocardiography.

Implications:

  • Contrast echocardiography improves the detection rate of left ventricular noncompaction.
  • Enhanced diagnostic accuracy can lead to earlier intervention and better patient outcomes.
  • This technique is vital for cases where standard echocardiography is inconclusive.