Schistosomiasis and signet ring cell carcinoma of the rectum
Mariana Canepa1, Paul T Fanta, Noel Weidner
1Department of Pathology, University of California, San Diego, 92103, USA.
Abstract:
A definitive link between Schistosoma hematobium infection and squamous cell carcinoma of the bladder has been identified. A weaker association between S japonicum infection and colorectal neoplasia has been proposed, although reports are limited to case reports, a case series, and epidemiologic studies. Virtually all cases presented in the literature describe intestinal-type adenocarcinoma occurring in association with S japonicum. We here describe a 40-year-old male Filipino patient with signet ring cell carcinoma of the rectum and evidence of infection by S japonicum.
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