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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Intraocular coccidioidomycosis simulating a neoplasm.

Devron H Char¹, J Brooks Crawford, George Bertolucci

¹The Tumori Foundation, 45 Castro Street, Suite 309, San Francisco, CA 94114, USA. devron@tumori.org

The British Journal of Ophthalmology

|May 7, 2011

Summary

This summary is machine-generated.

Coccidioidomycosis, a fungal infection, can mimic eye tumors. A case report details a 10-year-old girl whose painful, blind eye was removed due to this condition.

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Area of Science:

Ophthalmology
Infectious Diseases
Mycology

Background:

Coccidioidomycosis is a fungal infection endemic to arid regions of the Americas.
Intraocular involvement of Coccidioidomycosis is rare but can present with diverse clinical manifestations.
Distinguishing fungal endophthalmitis from intraocular neoplasms is crucial for appropriate management.

Observation:

A 10-year-old girl presented with symptoms suggestive of an intraocular tumor.
Ophthalmologic examination revealed a blind and painful eye.
Histopathological examination of the removed eye confirmed Coccidioidomycosis infection.

Findings:

The intraocular mass was definitively diagnosed as Coccidioidomycosis, not a neoplasm.
The fungal infection led to irreversible vision loss and ocular pain.
Enucleation was performed due to the severity and non-treatable nature of the intraocular infection.

Implications:

This case highlights the importance of considering Coccidioidomycosis in the differential diagnosis of intraocular masses, especially in endemic areas.
Early recognition and appropriate treatment of ocular Coccidioidomycosis can potentially prevent severe complications like blindness and the need for enucleation.
Further research into diagnostic modalities and therapeutic strategies for intraocular fungal infections is warranted.