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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Related Experiment Video

Updated: Jun 2, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
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MammoSite multilumen catheter: dosimetry considerations.

Akkamma Ravi1, Susan Lee, Karen Karsif

  • 1Department of Radiation Oncology, New York Hospital Queens, Flushing, NY 11355, USA. akr9001@med.cornell.edu

Journal of Cancer Research and Therapeutics
|May 7, 2011
PubMed
Summary

The MammoSite multilumen (ML) balloon offers dosimetric advantages for breast brachytherapy, improving dose coverage and reducing skin and rib doses when critical structures are near the target volume.

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Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Breast Surgery

Background:

  • Accelerated partial breast irradiation (APBI) is an option for early-stage breast cancer.
  • Brachytherapy delivers radiation from within the breast.
  • The MammoSite balloon is a common brachytherapy device.

Purpose of the Study:

  • To compare the dosimetric performance of the MammoSite multilumen (ML) balloon versus the single lumen (SL) device.
  • To evaluate dose distribution and coverage for breast brachytherapy planning.

Main Methods:

  • Two treatment plans were created for each patient using the MammoSite ML balloon.
  • The first plan (SL) utilized only the central lumen.
  • The second plan (ML) incorporated additional lumens for dose optimization.

Main Results:

  • The ML plan demonstrated improved dose coverage at the applicator tip and base.
  • Reduced skin and rib doses were observed with the ML plan when these structures were within 7 mm (skin) and 1 cm (rib) of the target.
  • No significant dose reduction to normal structures was noted when distances were greater than 1 cm.

Conclusions:

  • The MammoSite ML balloon can achieve better dosimetric goals in APBI.
  • Optimal dose delivery is enhanced when critical structures like skin and ribs are in close proximity to the target volume.
  • The ML device has the potential to minimize long-term toxicities such as rib discomfort and skin/fat necrosis.