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08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Malignant melanoma arising in a nevus spilus
C Angit1, N Khirwadkar, R M Azurdia
1Dermatology, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, United Kingdom.
Dermatology Online Journal
|May 10, 2011
Summary
Malignant melanoma rarely develops in nevus spilus, a congenital pigmented skin lesion. This case highlights a melanoma arising in a lifelong nevus spilus in a 65-year-old woman.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Nevus spilus, a congenital pigmented lesion, presents as macules and papules with hyperpigmentation.
- Malignant transformation within nevus spilus is an uncommon clinical event.
Observation:
- A 65-year-old woman presented with a suspicious lesion within a nevus spilus present since birth.
- The nevus spilus exhibited characteristic dark pigmentation and hyperpigmentation.
Findings:
- Histopathological examination confirmed the presence of malignant melanoma arising within the nevus spilus.
- This represents a rare occurrence of melanoma developing in a congenital nevus spilus.
Implications:
- Early detection and vigilance are crucial for melanomas arising in nevus spilus.
- Understanding the malignant potential of nevus spilus aids in patient management and risk assessment.
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