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Updated: Jun 2, 2026

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Published on: March 11, 2016
[Imaging evaluation of renal function: principles and limitations]
P-H Vivier1, M Dolores, J Le Cloirec
1Service de Radiologie, CHU Charles-Nicolle, 1 rue de Germont, 76031 Rouen cedex, France. pierre-hugues.vivier@chu-rouen.fr
Abstract:
The kidney performs multiple functions. Glomerular filtration is the most studied of these functions. In clinical practice, the surgical indication for patients with unilateral uropathy is frequently based on the split renal function as demonstrated by scintigraphy. MRI is not yet validated as a technique but nonetheless offers an interesting non-radiating alternative to achieve both morphological and functional renal evaluation. Recent pulse sequences such as diffusion, arterial spin labeling, and blood oxygenation dependent imaging may also provide additional information. CT and US remain of limited value for the evaluation of renal function.
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