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Updated: Jun 2, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Periaortic inflammation after endovascular aneurysm repair
Badri Vijaynagar1, Greg S McMahon, Mark J McCarthy
1Vascular Surgery, University Hospitals of Leicester NHS Trust, Leicester, UK. badrivv@aol.com
Periaortitis, an inflammation around the aorta, can rarely occur after endovascular aneurysm repair (EVAR). Prompt ureteric stenting and medical therapy can prevent kidney damage from this complication.
Area of Science:
- Vascular Surgery
- Nephrology
- Inflammatory Diseases
Background:
- Inflammatory abdominal aortic aneurysms typically resolve post-repair.
- Retroperitoneal fibrosis de novo after endovascular aneurysm repair (EVAR) is rarely documented.
Observation:
- A 63-year-old male developed periaortic inflammation and left ureteric obstruction 9 months post-EVAR for an abdominal aortic aneurysm.
- Symptoms included left loin pain and elevated inflammatory markers.
Findings:
- Ureteric stenting successfully resolved hydronephrosis.
- Periaortitis significantly improved with a combination of steroid and tamoxifen therapy.
Implications:
- Periaortitis causing renal impairment is a rare but serious complication of EVAR.
- Early diagnosis and intervention, including ureteric stenting, are crucial for preventing long-term renal damage.
- Steroid and tamoxifen offer a treatment strategy for periaortitis and recurrence prevention.
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