Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Decision Making: Traditional Method01:14

Decision Making: Traditional Method

The process of hypothesis testing based on the traditional method includes calculating the critical value, testing the value of the test statistic using the sample data, and interpreting these values.
First, a specific claim about the population parameter is decided based on the research question and is stated in a simple form. Further, an opposing statement to this claim is also stated. These statements can act as null and alternative hypotheses, out of which a null hypothesis would be a...
Null and Alternative Hypotheses01:16

Null and Alternative Hypotheses

The actual hypothesis testing begins by considering two hypotheses. They are termed  the null hypothesis and the alternative hypothesis. These hypotheses contain opposing viewpoints.
The null hypothesis, denoted by H0 is a statement of no difference between the variables—they are not related. This can often be considered the status quo. As  a result if you cannot accept the null, it requires some action.
The alternative hypothesis, denoted by H1 or Ha, is a claim about the population that is...
Testing a Claim about Population Proportion01:24

Testing a Claim about Population Proportion

A complete procedure for testing a claim about a population proportion is provided here.
There are two methods of testing a claim about a population proportion: (1) Using the sample proportion from the data where a binomial distribution is approximated to the normal distribution and (2) Using the binomial probabilities calculated from the data.
The first method uses normal distribution as an approximation to the binomial distribution. The requirements are as follows: sample size is large...
Statistical Analysis: Overview01:11

Statistical Analysis: Overview

When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regional Analgesia for Truncal Surgeries: Reply.

Anesthesiology·2026
Same author

2026 American Society of Anesthesiologists Practice Guideline on Perioperative Pain Management Using Local and Regional Analgesia for Cardiothoracic Surgeries, Mastectomy, and Abdominal Surgeries.

Anesthesiology·2025
Same author

Hypotension prediction index smart alerts and trends to improve compliance with goal-directed hemodynamic therapy: a feasibility study.

BMC anesthesiology·2025
Same author

Updated Findings From the Anesthesia Closed Claims Project.

International anesthesiology clinics·2025
Same author

Perioperative Care of Older Adults: Reply.

Anesthesiology·2025
Same author

Erratum: Identifying Variation in Intraoperative Management of Brain-Dead Organ Donors and Opportunities for Improvement: A Multicenter Perioperative Outcomes Group Analysis.

Anesthesia and analgesia·2025
Same journal

Reimagining cardiac surgery-the emerging role of prehabilitation and risk optimization.

Best practice & research. Clinical anaesthesiology·2026
Same journal

Prehabilitation and enhanced recovery after cardiac surgery.

Best practice & research. Clinical anaesthesiology·2026
Same journal

The role of biomarkers in the preoperative evaluation of cardiac surgical patients - A narrative review.

Best practice & research. Clinical anaesthesiology·2026
Same journal

Magic in a bottle? A Focused review of factor concentrates for the intraoperative treatment of acquired coagulopathy - Fibrinogen concentrate, prothrombin complex concentrate, and recombinant activated factor VII.

Best practice & research. Clinical anaesthesiology·2025
Same journal

ESAs in perioperative anemia management: Who, what, how and why?

Best practice & research. Clinical anaesthesiology·2025
Same journal

Does patient blood management represent good value for money?

Best practice & research. Clinical anaesthesiology·2025
See all related articles

Related Experiment Videos

Closed claims' analysis.

Julia Metzner1, Karen L Posner, Michelle S Lam

  • 1Department of Anesthesiology & Pain Medicine, Box 356540, University of Washington, Seattle, WA 98195-6540, USA. metznj@u.washington.edu

Best Practice & Research. Clinical Anaesthesiology
|May 10, 2011
PubMed
Summary
This summary is machine-generated.

Anesthesia claims data show a shift from surgical to pain management injuries. Key risks include regional blocks, respiratory, and cardiovascular events, impacting patient safety.

Related Experiment Videos

Area of Science:

  • Anesthesiology
  • Patient Safety Research
  • Medical Malpractice Analysis

Background:

  • The American Society of Anesthesiologists (ASA) established the Closed Claims database in 1985 to analyze anesthesia-related injuries.
  • The database now contains 8954 claims, with 5230 claims recorded since 1990, providing extensive data on anesthesia complications.

Purpose of the Study:

  • To review recent findings and clinical implications of anesthesia injuries.
  • To examine trends in claims related to surgical anesthesia, pain management, and obstetric anesthesia.
  • To identify common complications and damaging events associated with anesthesia care.

Main Methods:

  • Analysis of the American Society of Anesthesiologists (ASA) Closed Claims database.
  • Review of trends in anesthesia claims over several decades, focusing on the 2000s.
  • Categorization of claims by type of anesthesia (surgical, pain management, obstetric) and damaging events.

Main Results:

  • Claims for surgical anesthesia have decreased, while claims for acute and chronic pain management have increased.
  • In the 2000s, chronic pain management accounted for 18% of claims, acute pain management for 9%, and obstetrical anesthesia for 8%.
  • Monitored anesthesia care (MAC) claims increased to 10% in the 2000s, while regional anesthesia represented 19% of claims.
  • The most frequent complications included death (26%), nerve injury (22%), and permanent brain damage (9%).
  • Common damaging events were regional-block-related (20%), respiratory (17%), cardiovascular (13%), and equipment-related (10%).

Conclusions:

  • Anesthesia practice has seen a significant shift in claim types, with a rise in pain management-related injuries.
  • Understanding the trends in complications and damaging events is crucial for improving patient safety in various anesthesia settings.
  • Further examination of injuries related to difficult airway management, MAC, non-operating room locations, obstetric anesthesia, and chronic pain management is warranted.