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Lung cancer with skin metastasis
1Thoracic Surgery Service, Wilkes-Barre General Hospital, Pa.
Chest
|March 1, 1990
Summary
Cutaneous metastasis from lung cancer is a rare but significant finding. Early skin lesion biopsy is crucial for diagnosis and prognosis in patients with lung cancer.
Area of Science:
- Oncology
- Dermatology
- Pulmonology
Background:
- Cutaneous metastasis from lung cancer is uncommon.
- Understanding its clinical significance is vital for physicians.
- This study reviews cases of lung cancer with skin involvement.
Observation:
- Eight patients with cutaneous lung cancer metastasis were treated over 30 months.
- Skin lesions presented as the initial symptom in three patients and were concurrent with lung mass in three others.
- Histopathology revealed small-cell, squamous cell, and large-cell undifferentiated lung carcinomas.
Findings:
- Seven of eight primary lung cancers were located in the upper lobes.
- Six patients presented with occult visceral metastases at the time of skin biopsy.
- Survival was poor, with only one patient living over six months post-skin metastasis.
Implications:
- Biopsy of new skin lesions is essential, especially in smokers or those with a history of lung cancer.
- Cutaneous metastasis indicates advanced disease and poor prognosis.
- Early detection through skin biopsy can aid in diagnosis and management planning.