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Delivery of Proteins, Peptides or Cell-impermeable Small Molecules into Live Cells by Incubation with the Endosomolytic Reagent dfTAT
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Tat-mediated delivery of heterologous macromolecules into living cells

J Barsoum1, C Moore, J Seery

  • 1Biogen Inc., 14 Cambridge Center, Cambridge, MA 02142, USA.

Restorative Neurology and Neuroscience
|May 10, 2011
PubMed
Abstract

No abstract available in PubMed .

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Microbial communities are dynamic environments where cell lysis releases free DNA into the surroundings. Other cells can take up this extracellular DNA through a process known as transformation.When a cell incorporates this foreign DNA into its genome, resulting in genetic modification, the process is known as transformation. Cells capable of this process are termed competent. Competence can be natural, as observed in certain bacteria and archaea, or artificially induced in the...

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