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Related Experiment Video

Updated: Jun 2, 2026

Separation of Mouse Embryonic Facial Ectoderm and Mesenchyme
08:36

Separation of Mouse Embryonic Facial Ectoderm and Mesenchyme

Published on: April 12, 2013

A case report of complete chorioamniotic membrane separation.

Gen Ishikawa1, Misao Satomi, Tomoko Inagawa-Ichikawa

  • 1Division of Reproductive Medicine, Perinatology and Gynecologic Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan. gen-ishi@nms.ac.jp

Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
|May 10, 2011
PubMed
Summary

Chorioamniotic membrane separation (CMS) is a rare condition where fetal membranes separate. This case highlights its detection via ultrasound and successful management, leading to a healthy infant.

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Area of Science:

  • Perinatology
  • Reproductive Medicine
  • Fetal Medicine

Background:

  • Chorioamniotic membrane separation (CMS) is a pathological condition arising from the separation of the chorionic and amniotic membranes.
  • This separation can occur spontaneously or secondary to invasive intrauterine procedures, potentially leading to severe pregnancy complications.

Observation:

  • A case of complete CMS was diagnosed at 29 weeks gestation via routine ultrasonography.
  • The diagnosis was made in the absence of concerning fetal status or intrauterine abnormalities, following a prior amniocentesis at 16 weeks.
  • Ultrasonography revealed a free-floating membranous structure within the intra-amniotic cavity.

Findings:

  • Prenatal diagnosis of complete CMS was confirmed by pathological examination post-delivery.

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  • The pregnancy was managed with precautionary monitoring and concluded with an elective cesarean section at 37 weeks.
  • The infant was delivered without complications.

    • Implications:

    • This case underscores the importance of routine ultrasonography in detecting conditions like CMS.
    • Accurate prenatal diagnosis and vigilant management are crucial for favorable pregnancy outcomes in cases of CMS.
    • Understanding the etiology and potential complications of CMS aids in optimizing obstetric care and patient counseling.